Multiple myeloma is a pathology of the bone marrow in which the increase in a type of cells (plasma cells) determines the appearance in the serum of a variable amount of damage to numerous structures: among these the bones undergo fractures, the kidneys can develop insufficiency and the bone marrow becomes insufficient, with anemia, thrombocytopenia, and leukopenia.

The evolution is not favorable and the treatments allow, today, only the control of the disease, but not the cure. The latter seems to be obtainable, in a variable percentage of cases, only with traditional allogeneic or non-myeloablative transplantation.